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Datum kreiranja: 15.05.2017.

Katarina Tomović

Dodatne informacije

  • Lični podaci

  • Datum rođenja: 29.07.1991.
  • Mesto rođenja: Prokuplje

  • Obrazovanje

  • Fakultet: Medicinski fakultet Univerziteta u Nišu
  • Odsek / Grupa / Smer: Farmacija
  • Godina diplomiranja: 2015.

  • Spisak publikacija

  • Radovi u časopisima sa IMPACT faktorom:


    1. Tomović Pavlović, K., Kocić, G., Šmelcerović, A. (2024) Myt1 kinase inhibitors - Insight into structural features, offering potential frameworks. Chemico-Biological Interactions 391, 110901.



    2. Kocic, G., Hadzi-Djokic, J., Colic, M., Veljkovic, A., Tomovic, K., Roumeliotis, S., Smelcerovic, A., Liakopoulos, V. (2023) The role of nucleases cleaving TLR3, TLR7/8 and TLR9 ligands, dicer RNase and miRNA/piRNA proteins in functional adaptation to the immune escape and xenophagy of prostate cancer tissue. International Journal of Molecular Sciences 24, 509. 

    3. Cherneva, E., Atanasova, M., Šmelcerović, Ž., Tomović, K., Buyukliev, R., Šmelcerović, A., Bakalova, A. (2022) 3′-Aminothiocyclohexanespiro-5′-hydantoin and its Pt(II) complex-Synthesis, cytotoxicity and xanthine oxidase inhibitory activity. Inorganics 10(10), 175. 

    4. Kocic, G., Gajic, M., Tomovic, K., Hadzi-Djokic, J., Anderluh, M., Smelcerovic, A. (2021) Purine adducts as a presumable missing link for aristolochic acid nephropathy related cellular energy crisis, potential anti-fibrotic prevention and treatment. British Journal of Pharmacology 178, 4411-4427. 

    5. Tomovic, K., Ilic, B.S., Smelcerovic, A. (2021) Structure-activity relationship analysis of cocrystallized gliptin-like pyrrolidine, trifluorophenyl, and pyrimidine-2,4-dione dipeptidyl peptidase 4 inhibitors. Journal of Medicinal Chemistry 64, 9639-9648.

    6. Smelcerovic, A., Kocic, G., Gajic, M.Z., Tomovic, K., Djordjevic, V., Stankovic-Djordjevic, D., Anderluh, M. (2020) DPP-4 inhibitors in the prevention/treatment of pulmonary fibrosis, heart and kidney injury caused by COVID-19 - a therapeutic approach of choice in type 2 diabetic patients? Frontiers in Pharmacology 11, 1185. 

    7. Cherneva, E., Atanasova, M., Buyukliev, R., Tomovic, K., Smelcerovic, Z., Bakalova, A., Smelcerovic, A. (2020) 3'-Methyl-4-thio-1H-tetrahydropyranspiro-5'-hydantoin platinum complex as novel potent anticancer agent and xanthine oxidase inhibitor. Archiv der Pharmazie 353, e2000039. 

    8. Tomovic, K., Ilic, B.S., Miljkovic, M., Dimov, S., Yancheva, D., Kojic, M., Mavrova, A.T., Kocic, G., Smelcerovic, A. (2020) Benzo[4,5]thieno[2,3‐d]pyrimidine phthalimide derivative, one of the rare noncompetitive inhibitors of dipeptidyl peptidase‐4. Archiv der Pharmazie 353, 1900238.

    9. Tomovic, K., Ilic, B.S., Smelcerovic, Z., Miljkovic, M., Yancheva, D., Kojic, M., Mavrova, A.Ts., Kocic, G., Smelcerovic, A. (2020) Benzimidazole-based dual dipeptidyl peptidase-4 and xanthine oxidase inhibitors. Chemico-Biological Interactions 315, 108873.

    10. Anderluh, M., Kocic, G., Tomovic, K., Kocic, H., Smelcerovic, A. (2019) DPP-4 inhibition: А novel therapeutic approach to the treatment of pulmonary hypertension? Pharmacology and Therapeutics 201, 1-7. 

    11. Tomovic, K., Lazarevic, J., Kocic, G., Deljanin-Ilic, M., Anderluh, M., Smelcerovic, A. (2019) Mechanisms and pathways of anti-inflammatory activity of DPP-4 inhibitors in cardiovascular and renal protection. Medicinal Research Reviews 39(1), 404-422. 

    12. Smelcerovic, A., Lazarevic, J., Tomovic, K., Anastasijevic, M., Jukic, M., Kocic, G., Anderluh, M. (2019) An overview, advantages and therapeutic potential of non-peptide positive allosteric modulators of glucagon-like peptide-1 receptor. ChemMedChem 14(5), 514-521.

    13. Damnjanovic, I., Kocic, G., Najman, S., Stojanovic, S., Tomovic, K., Ilic, B., Veljkovic, A., Pesic, S., Smelcerovic, A. (2019) Possible molecular mechanisms and pathways involved in BH3 mimetic activity of alpha-lipoic acid on human colon cancer cell line. Farmacia 67(2), 226-234.

    14. Šmelcerović, A., Tomović, K., Šmelcerović, Ž., Petronijević, Ž., Kocić, G., Tomašič, T., Jakopin, Ž., Anderluh, M. (2017) Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity. European Journal of Medicinal Chemistry 135, 491-516.

    15. Kocic, G., Veljkovic, A., Kocic, H., Colic, M., Mihajlovic, D., Tomovic, K., Stojanovic, S., Smelcerovic, A. (2017) Depurinized milk downregulates rat thymus MyD88/Akt/p38 function, NF-κB-mediated inflammation, caspase-1 activity but not the endonuclease pathway: in vitro/in vivo study. Scientific Reports 7: Article number: 41971; doi: 10.1038/srep41971

    16. Kocic, G., Tomovic, K., Kocic, H., Sokolovic, D., Djordjevic, B., Stojanovic, S., Arsic, I., Smelcerovic, A. (2017) Antioxidative, membrane protective and antiapoptotic effects of melatonin, in silico study of physico-chemical profile and efficiency of nanoliposome delivery compared to betaine. RSC Advances 7, 1271-1281.

    17. Anderluh, M., Kocic, G., Tomovic, K., Kocic, R., Deljanin-Ilic, M., Smelcerovic, A. (2016) Cross-talk between the dipeptidyl peptidase-4 and stromal cell-derived factor-1 in stem cell homing and myocardial repair: Potential impact of dipeptidyl peptidase-4 inhibitors. Pharmacology and Therapeutics 167, 100-107.

    18. Vukelić-Nikolić, M., Kolarević, A., Tomović, K., Yancheva, D., Cherneva, E., Najman, S., Šmelcerović, A. (2015) Effects on MC3T3-E1 cells and in silico toxicological study of two 6-(propan-2-yl)-4-methyl-morpholine-2,5-diones. Natural Product Communications 10(8), 1423-1426.
  • Radovi u ostalim časopisima:

    1. Tomović, K., Mrmošanin, J., Yancheva, D., Mavrova, A.Ts., Šmelcerović, A. (2020) In vitro antioxidant properties of 2-imino-benzimidazole and 1,3-thiazolo[3,2-a]benzimidazolone derivative. Acta Facultatis Medicae Naissensis 37(4), 381-386.

    2. Tomović, K., Kocić, G., Šmelcerović, A. (2019) Potential dual mechanism of hypouricemic acitivity of DPP-4 inhibitors with purine-based scaffold. Acta Medica Medianae 58(1), 50-63.

    3. Damnjanović, I., Kocić, G., Najman, S., Stojanović, S., Tomović, K., Ilić, B., Veljković, A., Šmelcerović, A. (2018) Molecular mechanisms of potential synergistic effect of ketoprofen and meloxicam with conventional cytostatics in human cervix cancer cell line. Acta Medica Medianae 57(4), 52-59.

    4. Šmelcerović, A., Šmelcerović, Ž., Tomović, K., Kocić, G., Đorđević, A. (2017) Secondary metabolites of Hypericum L. species as xanthine oxidase inhibitors. Acta Facultatis Medicae Naissensis 34(4), 275-281.

    5. Šmelcerović, Ž., Tomović, K., Yancheva, D., Cherneva, E., Kocić, G., Petronijević, Ž. (2016) Xanthine oxidase inhibitory properties and in silico study of three N-(α-bromoacyl)-α-amino esters. Acta Medica Medianae 55(4), 14-20.
  • Radovi na naučnim skupovima međunarodnog značaja:

    1. Tomović, K. DPP-4 inhibitors in the prevention/treatment of pulmonary fibrosis, heart and kidney injury caused by COVID-19: Mechanisms of action. Proceeding of the 5th International Cardionephrology and Hypertension Congress "KARNEF 2021", Pirot, Serbia, September 2021, p. 145-146.



    1. Tomović, K., Lazarević, J., Šmelcerović, Ž., Kocić, G., Šmelcerović, A. Dipeptidyl peptidase-4 and xanthine oxidase dual inhibition - potentiation of hypouricemic and antioxidative effects. Proceeding of the 4th International Congress of Cardionephrology and Hypertension "KARNEF 2019", Ribarska Banja, Serbia, May 2019, p. 185.




    2. Tomović, K., Kocić, G., Anderluh, M., Šmelcerović, A. Beneficial effects of dipeptidyl peptidase-4 inhibitors on vascular dysfunction. Proceeding of the XXV EFMC International Symposium on Medicinal Chemistry, Ljubljana, Slovenia, September 2018, p. 258.




    3. Šmelcerović, A., Šmelcerović, Ž., Tomović, K., Kocić, G., Yancheva, D., Ts. Mavrova, A. 2-Imino-benzimidazoles and 1,3-thiazolo[3,2-a]benzimidazolones as xanthine oxidase inhibitors. Proceeding of the 3rd International Cardionephrology and Hypertension Congress "Cardionephrology Up To Date", Pirot, Serbia, May 2017, pp. 156-157.




    4. Tomović, K., Kocić, G., Deljanin-Ilić, M., Lazarević, J., Anderluh, M., Šmelcerović, A. DPP-4 inhibitors, not only antidiabetic, but also cardiovascular and renal protective agents. Proceeding of the 3rd International Cardionephrology and Hypertension Congress "Cardionephrology Up To Date", Pirot, Serbia, May 2017, pp. 158-159.
  • Radovi na domaćim naučnim skupovima:


      1. Bakalova, A., Atanasova, M., Buyukliev, R., Tomović, K., Marković, A., Šmelcerović, Ž., Šmelcerović, A., Cherneva, E. Xanthine oxidase and deoxyribonuclease i inhibitory properties of 5-methyl-5-(2-thiomethyl) ethyl hydantoin and its Pt (IV) complex. 8th Congress of Pharmacy with international participation "Escape from the Pandemonium, Pharmaceutical Restart 2023", Borovets, Bulgaria, April 2023.

      2. Tomović, K., Kocić, G., Šmelcerović, A. Multitarget drug - advantages and challenges. Congress PharmaNaissa I, Niš, Serbia, September 2022, published in Acta Medica Medianae 61(Suppl. 3) pp. 49-50.

      3. Marković, A., Tomović, K., Kocić, G., Šmelcerović, A. Drug development based on the inhibition of medically important enzymes. Congress PharmaNaissa I, Niš, Serbia, September 2022, published in Acta Medica Medianae 61(Suppl. 3) pp. 31-32.

      4. Yancheva, D., Mavrova, A., Anichina, K., Argirova, M., Anastasova, N., Lumov, N., Tomovic, K., Markovic, A., Guncheva, M., Smelcerovic, A. Exploring the potential of benzimidazole core for development of multi-target agents. National conference with international participation "Innovations in drug molecules", Hisarya, Bulgaria, July 2022, pp. 19-21.

      5. Cherneva, E., Tomović, K., Šmelcerović, Ž., Šmelcerović, A., Buykliev, R., Bakalova, A. 3'-Methyl-4-thio-1H-tetrahydropyranspiro-5'-hydantoin and its Pt(IV) and Pd(IV) complexes as novel potent xanthine oxidase inhibitors. 7th Congress of Pharmacy with international participation ''Pharmaceutical Altitudes'', supported by Bulgarian Pharmaceutical Union, Borovets, Bulgaria, November 2019, pp. 144-145.

      6. Cherneva, E., Šmelcerović, Ž., Tomović, K., Šmelcerović, A., Buykliev, R., Bakalova, A. Xanthine oxidase inhibitory activity of thiocyclohexanespiro-5'-hydantoin, 3'-aminothiocyclohexanespiro-5'-hydantoin and their Pt(II) complexes. 7th Congress of Pharmacy with international participation ''Pharmaceutical Altitudes'' supported by Bulgarian Pharmaceutical Union, Borovets, Bulgaria, November 2019,  pp. 146-147.

      7. Tomović, K., Kocić, G., Šmelcerović, A. GLP-1 dependent/independent effects of DPP-4 inhibitors in the pathobiology of lung vascular injury. First symposium of the Section of pharmaceutical sciences of the Pharmaceutical Association of Serbia ''From idea to clinical application: Current pharmaceutical research'', Novi Sad, Serbia, September 2019, published in Arhiv za farmaciju 69(Suppl. 4) pp. S77-S78.
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